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Power of the study
 
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Power of the study

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(@rahima-noor)
Posts: 30
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What is “Power” in Research?

The power of a study is the probability that your statistical test will correctly reject the null hypothesis when the alternative hypothesis is actually true.

  • In other words, it's your study’s ability to detect a true effect.

  • It is mathematically defined as:
    Power = 1 – β, where β is the probability of making a Type II error (false negative).

🧪 Why Does Study Power Matter in Research?

  1. Avoids False Conclusions
    An underpowered study may fail to detect real differences or associations, leading to misleading results.

  2. 📈 Supports Evidence-Based Practice
    Especially in clinical research, well-powered studies contribute to treatment guidelines and medical decision-making.

  3. 📉 Prevents Resource Waste
    Time, money, and effort are wasted on studies that are unlikely to produce meaningful results.

  4. 📊 Enhances Publication Quality
    Journals often require a power analysis to demonstrate that a study is methodologically sound.

🧠 Key Factors Affecting Power:

  • Sample Size: More participants = more power

  • Effect Size: Larger true differences = easier to detect

  • Significance Level (α): Lower alpha = lower power

  • Variability in Data: More variation = harder to detect effects

  • Study Design: Matched pairs, crossovers, or repeated measures can increase power

💡 Typical Threshold:

Most research aims for at least 80% power, meaning there's an 80% chance your study will detect a true effect (if it exists).

🔢 Example:

Let’s say you are studying whether a new drug reduces blood pressure compared to a standard drug.

  • Your estimated effect size (difference between means) = 5 mmHg

  • You set α = 0.05 (5% chance of Type I error)

  • You want 80% power to detect this difference

  • You calculate (using G*Power or a sample size formula) that you need 150 patients in each group.

Now imagine you only enroll 50 per group.
Your power drops to ~45%, meaning even if the drug truly works, there’s more than a 50% chance your study won’t detect it. That’s a waste of time, resources, and opportunity—and potentially harmful if decisions are based on a false negative.


🛠️ What Affects Power?

  • Sample Size ↑ → Power

  • Effect Size ↑ → Power

  • Variability (Standard Deviation) ↑ → Power

  • Alpha Level (Significance Threshold) ↓ → Power

  • Study Design Efficiency ↑ → Power

 
Posted : 15/05/2025 11:31 am
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